10.20.2020

ibuprofen

How much ibuprofen can kill you? Animal research shows that the lethal dose that kills 50% of test animals (LD50) of oral ibuprofen is 636 mg/kg. If this value is applied to humans, it may take 191 tablets (200mg/tablet) or a total of 38,160 mg for a 60-kg man to die from acute ibuprofen overdose. The effects of ibuprofen at lesser doses (600-800mg) also include upset stomach, which can lead to internal bleeding and death, over a long time. Taking higher doses (1200-1600mg) can make you sick and throw up, but not enough to kill you at once. ----What Can Ibuprofen Overdose Do to You? ---1: Digestive Disorder Ibuprofen is toxic and can damage the intestinal tract, which may cause severe stomach pain and internal bleeding of the stomach or intestines. Heartburn can also be caused as high dose of ibuprofen can increase the acid production in the stomach. You may also experience diarrhea and bloating. ---2: Difficult Breath Ibuprofen, when taken in large doses, can depress respiration and cause difficult or slow breathing, accompanied by wheezing and cough. ---3: Ringing in the Ears Some people experience buzzing or ringing in their ears (tinnitus) after taking large doses of ibuprofen. Other sensations include hissing, whistling, clicking, or roaring in the ears. These may affect one or both of your ears and can result in difficulty hearing or concentrating. ---4: Blurred Vision Vision problems can occur after ingesting too much of the drug. Blurring or seeing double can make you dizzy, lightheaded and unable to walk normally. ---5: Drowsiness Drowsiness is another possible side effect of taking excessive amounts of ibuprofen. In severe cases, you can faint or lose consciousness after an overdose. ---6: Confusion A person may appear confused, incoherent (difficult to understand), or agitated after taking too much ibuprofen. You can also develop headaches and poor coordination. ---7: Convulsions Tremors, convulsions, or seizures characterized by uncontrollable body shaking can also occur after ingesting large amounts of ibuprofen. These may be followed by loss of consciousness and coma. ------What to Do If Someone Overdoses on Ibuprofen Knowing how many ibuprofens does it take to die and what overdose of it can do for you is not enough, know also what to do if overdose. Call the Poison Help line (1-800-222-1222) and seek emergency medical attention. Symptoms of overdose may include severe stomach pain, nausea, vomiting, drowsiness, profuse sweating, bloody/black stools, shallow breathing, coughing up of blood, loss of consciousness, or coma. In the emergency room, you may be given liquid charcoal to absorb the drug and prevent it from entering your systemic circulation. Gastric lavage may be done if you have taken potentially life threatening doses. Ibuprofen overdose can also land you into a mental hospital if you are suspected of attempted suicide. ---why my sudden interest? saw a FB post that someone I know was depressed and overdosed on ibuprofen, which I didn't realize was a thing. to me, suicide would be drinking bleach or putting a gun in your mouth or a noose around your neck or slitting open a major artery. I am a big believer in OTC meds and treat myself liberally. not a bottle at a time, mind you, but I never thought about the possibility of overdose. guess I should be minding my p's and q's here. danger is afoot.

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